Abstract

NANOMEDICINE IN DIABETES MELLITUS: A REVIEW

Shubham Marbade*, J. V. Vyas, V. V. Paithankar and A. M. Wankhede

ABSTRACT

Diabetes mellitus (DM) could be major public health issue affecting more than 400 million people worldwide. It is a metabolic disorder characterized by hyperglycaemia, glycosuria, lipidaemia, negative nitrogen balance and generally ketonaemia. Nanotechnology refers to an rising field of science that features synthesis and development of various nanomaterials. These novel dosage forms defend them from catalytic degradation within the adverse gastrointestinal (GI) surrounding, whereas also enabling easy transport and improving the pharmacokinetics, bioavailability and therapeutic efficacy after administration. A computerized search was carried out through different databases. The medical applications for nanotechnology are enormous and could give medicine, including the treatment of diabetes. It is assumed to reduce the damage to the renal, pancreas, liver, and reproductive system caused by diabetes, by reducing oxidative stress and increase antioxidant, insulin sensitivity, and aldohexose utilization.

Keywords: Diabetes mellitus, Nanoparticles, Copper, Selenium, Zinc Oxide, Silver.