Abstract

CUBOSOMES: A NOVEL STRATEGIC APPROACH FOR DRUG DELIVERY

Ayush Chandra Mishra*, Ratnesh Chaubey and Chandan Kumar Singh

ABSTRACT

Cubosomes are biconjugate cubic phased preparations that have been reversed and exhibit unique physiochemical features. These are square and round shaped molecules with a core cubic lattice that are stable and have a honeycombed structure that separates internal compartments or aqueous channels. Cubosomes dispersion is biocompatible and bio adhesive. Cubosomes are adaptable systems due to their characteristics, and may be administered in a variety of methods, including oral, percutaneous, and Injectables. Cubosomes have a vast range of uses and are defined by a number of characteristics. People are interested in these unique systems as they can deliver hydrophilic, hydrophobic, and amphiphilic drugs with increased bioavailability and loading capacity. Cubosomes' lipids have a higher stability factor, which means the formulation will be more stable over time. The article discusses how Cubosomes are produced using several methods such as probe-ultra sonification and high-pressure homogenization. This article also shows the change in stages, as well as Cubosomes' tailored approach and neoterical uses, such as medications like flurbiprofen for ocular disorders, flurazepam for CNS difficulties, and so on. Also covered are the benefits and drawbacks of cubosomal medication delivery.

Keywords: Cubosomes, Cubic Lattice, Amphiphilic, Probe-ultra sonification, Loading Capacity, High Pressure Homogenization, Neoterical.