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Abstract

EVALUATION OF ANTICONVULSANT ACTIVITY OF HYDROALCOHOLIC EXTRACT OF MIMOSA PUDICA THORNS ON LABORATORY ANIMALS

GB Alaka Kar*, Susanta Kumar Rout and Debashisa Mishra

ABSTRACT

Objective: To investigate the anticonvulsant activity of hydroalcoholic extracts of leaves and roots of Mimosa Pudica Thorns and its fractions (Chloroform, ethyl acetate, methanol and aqueous) against pentylenetetrazole (PTZ), maximal electroshock (MES), Strychnine (STR), convulsions at different dose levels. Methods: The anticonvulsant effect of MES, PTZ, and STR induced seizure. Results: The extract at 200 and 400 mg/ kg, produced a significant (P

Keywords: Epilepsy, Mimosa pudica root extract, MES, PTZ model.


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