Abstract

EVALUATION OF ANTI-ANXIETY ACTIVITY OF BROMELAIN

*Sakshi Ahirwar, Saloni Chourasia, Asha Rani Pyati, Namrata Gupta,
Dr. Rajendra Bapna and Sandhya Sujane

ABSTRACT

Anxiety disorder is one of the most common mental ailment exhibitedby human. It is characterized by motor tension, sympathetic hyperactivity and apprehension and vigilance syndrome. A part from very few chemical remedies available like benzodiazepine and serotonin modulators, not much treated options are at hand that safely and effectively alleviate anxiety. Bromelain wad evaluated for its anti-anxiety activity in swiss albino mice at dose 200mg/kg and 400mg/kg body weight. Anti- anxiety was assessed by using elevated plus maze (EPM) model. Bromelain exhibit anxiolytic effect in experimental mice. So it is supports the use of bromelain as anxiolytic agents. Further investigation should made to elucidate the active constituent of responsible for the activity.

Keywords: Anxiety, Bromelain, Plus Maze model.