Abstract

A HISTORICAL OUTLOOK ON NIOSOMES WITH THEIR PARAMETERS: AN UPDATE REVIEW

Mohd. Faijan Mansoori*, Ram Narayan Prajapati, Nirmala Devi and Sakshi Tiwari

ABSTRACT

Liposomes, niosomes, proniosomes, transferosomes, ethosomes, and electrosomes are just a few of the targeted vesicular drug delivery carriers that have emerged in recent years. For transdermal medication administration, niosomes and proniosomes have the potential to be better carriers because they reduce side effects while also increasing therapeutic efficiency and bioavailability. Niosomes are non-ionic vesicles obtained with or without the inclusion of cholesterol or lipids when hydrated with synthetic nonionic surfactants. They can act as both amphipathic and lipophilic reservoirs. Stereoisomers, semi-isomers, and niosomes are prospective drug delivery vectors that are currently under investigation. Semi-disintegrable, semi-substructure, and niosomes are examples of delivery systems that are adaptable. Cancer, viral infections, and other disorders have been researched, and it has been discovered that controlled release and transport of niosomes are extremely effective in treating them.In contrast to conventional oral dosage forms, which suffer from low bioavailability, frequent high doses, and untargeted drug action, the transdermal drug delivery method was proven to be a highly successful solution.

Keywords: Niosomes, Compositions, Methods of Preparation, Factors affecting, Characterizations, and Applications.