Abstract

REVIEW ON THE CORONAVIRUS DISEASE COVID-19 ITS ETIOLOGY PATHOGENESIS, VIROLOGY, PREVENTION AND TREATMENT

Seema B. Kharwade*, Narendra G. Patre, Ajay D. Kshirsagar and Sudam G. Mule

ABSTRACT

Coronaviruses are necessary human and animal pathogens. At the end of 2019, a novel coronavirus was identified as the cause of a cluster of pneumonia cases that is respiratory ilness in Wuhan, a city in the Hubei Province of China. It quickly spread, resulting in an epidemic throughout China, followed by a global pandemic.[1] In Feb 2020, the WHO designated the disease COVID-19 or Coronavirus disease 2019. The initial infected individuals largely were mostly exposures to a seafood market in Wuhan. In the current research analysis, we performed a detailed depth of review that was widely obtainable to summarise pathogenesis and ongoing epidemic, epidemiological facts, diagnosis, disease control approaches and scenario of prevention.[2] This virus, designated selected as severe acute respiratory syndrome corona virus affected 8422 people largely in China and Hong Kong and caused 916 deaths (mortality rate 11%) before being contained.[3] First, three of the seven coronaviruses, particularly SARS-CoV, MERS-CoV, and SARS-CoV-2 are pathogenic specie . Coronaviruses (CoV) are a family of viruses known as Coronaviridae. The subfamily Coronavirinae has three genera alphacoronavirus, betacoronavirus and gammacoronavirus. The subfamily Torovirinae has two genera, torovirus and bafinivirus. CoV can result to diversity of conditions as mild as the common cold, fever and cough and as severe as pneumonia, respiratory distress kidney failure or may be death.[4]

Keywords: WHO; SARS-CoV-2; COVID-19; MERS.