Abstract

A REVIEW ON PLATELET RICH PLASMA (PRP) AND ITS APPLICATIONS

Rani Manju*

ABSTRACT

Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions.[1] Platelet activation plays a key role in the body's natural healing process. Platelets are known to aid in the healing process of all wounds and therefore the regeneration of cells. New data show that platelets release large doses of bioactive proteins, known as growth factors responsible for attracting macrophages, mesenchyme stem cells and osteoblasts which promote the removal of necrotic tissue and enhance tissue regeneration and repair. Platelets are responsible for the process of hemostasis, development of new connective tissue, and restoration of blood circulation. A blood specimen typically contains 93% RBC, 6% Platelets, and 1% WBC. The foundation for the benefits of Platelet Rich Plasma (PRP) is by inverting the blood ratio of RBC to 5%, and increasing platelets to 94% to stimulate recovery. PRP injection induces soft-tissue augmentation, activation of fibroblasts, and new collagen deposition, as well as new blood vessels and adipose tissue formation. They also improve burn scars, postsurgical scars, and acne scars.

Keywords: Plasma Treatment, PRP, Platelet Treatment.