Abstract

REVIEW ON FORMULATION AND STANDARDIZATION OF HERBAL LOZENGES

S. Ramya*, S. Shakila Banu, G. Krishnamoorthy and R. Senthamarai

ABSTRACT

The lozenges are palatable solid unit dosage form administered in the oral cavity. It is dissolved in mouth or pharynx and produces local or systemic effects. Lozenge dosage form is more beneficial method because of good patient compliance due to its taste, increased bioavailability, reduced gastric irritation, reduced first pass metabolism, and increased onset of action. The caramel based soft candy lozenges, hard candy lozenges, and compressed tablet lozenges are available in the market. Herbal formulations are used by mankind to cure various ailments and they are still very popular. Herbal lozenges were prepared by melting and moulding technique. The prepared herbal lozenges were subjected to various parameters like macroscopic evaluation, friability, hardness, uniformity of weight, disintegration time, pH, salt content, total sugar, test for heavy metals (lead, cadmium, mercury, arsenic), aflatoxins, shelf life, ash value, swelling index, moisture content, extractable matter, thin layer chromatography, UV spectrophotometry, etc which are comply with the standards mentioned in AYUSH Guidelines. This review covers more or less all aspects associated with the formulation and evaluation of the Herbal Lozenges and also throws light on various herbal lozenges available in the market.

Keywords: Herbal lozenges, Lozenges, Parameters, AYUSH, Standardization.