Abstract

A REVIEW ON CITALOPRAM

*Patil Riddhi Rajendra, Khalkar Pooja Dilip and Dhakne Radhika Bhagwan

ABSTRACT

A cataract is a condition where clouding of eyes naturally occurs. It acts as a major complication in case of diabetes mellitus. The present study investigates the effect of methanolic extract of Ziziphus xylopyrus fruition cataract induced by glucose. Ziziphus xylopyrus, a traditional folklore plant, has antioxidant, antiulcer properties. Goat eye lenses were divided into four groups. Group I lenses were incubated in artificial aqueous humor with glucose concentration of 5.5 mM (normal control). Group II lenses were incubated with glucose concentration of 55 mM (toxic control). Group III and IV lenses were incubated with glucose concentration of 55 mM along with methanolic extract of Ziziphus xylopyrus fruit.(50μg\ml) and (100 μg\ml). The entire lenses were subjected to photographic evaluation for opacity. The grades of opacity was 0, +++, +,++ in each group respectively. Thus, the goat lens could be used for testing of various anti-cataract agents.

Keywords: Anticataract, Antioxidant, Oxidative stress, SSRI.