A REVIEW ON SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL BENZIMIDAZOLE DERIVATIVES
Joshna Jose* and Dr. Presannakumaran P.N.
ABSTRACT
Benzimidazole is a heterocyclic aromatic organic compound. It is an important pharmacophore and a privileged structure in medicinal chemistry. The compound is bicyclic in nature which consists of the fusion of benzene and imidazole. A large variety of 2 substituted benzimidazoles have been found to possess antiulcer, anthelmintic, anti-inflammatory and HIV-1 reverse transcriptase inhibitor activities.
Keywords: Benzimidazole, Anti-inflammatory activity, Anti-microbial activity.
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