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HEPATOPROTECTIVE ACTIVITY OF FRESH FRUIT JUICE OF SYZYGIUM JAMBOS AGAINST ALCOHOL INDUCED HEPATOTOXICITY IN EXPERIMENTAL RATS
Harsha P. V.*, Kavyanjali K. V. and Ashoka Shenoy M.
ABSTRACT
The aim of present study was to investigate the Hepatoprotective activity of fresh fruit juice of Syzygium jambos in experimental rats against ethanol induced hepatotoxicity in rats. The efficacy of any hepatoprotective drug is essentially dependent on its capability of either reducing the harmful effects or in maintaining the normal hepatic physiological mechanism. Two doses 1ml/kg and 2ml/kg body weight p.o of the fruit juice were subjected for the evaluation of Hepatoprotective potential against ethanol (2ml/100g) induced liver injury. Silymarin (25mg/kg) was used as a standard drug. The parameters like SGPT, SGOT, ALP, Total Bilirubin and endogenous enzymes were estimated to assess the liver functions. Orally administered doses of 1 ml/kg and 2 ml/kg of fresh fruit juice of Keywords: Hepatoprotective activity, Alcohol Induced Hepatotoxic activity, Syzygium jambos, Silymarin. [Download Article] [Download Certifiate] |