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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES OF GLIBENCLAMIDE

Pooja Jatav* and Wasim Raza Ali Khan

ABSTRACT

The aim of this work is to formulate and evaluate transdermal patches containing glibenclamide as active pharmaceutical ingredient. The objective of the present investigation was to evaluate the transdermal films of glibenclamide to its applicability to reduce the dose of the drug. The patches were prepared with the help of a various polymers (Ethyl cellulose, HPMC, and Carbopol 934). The patches that contained carbopol were more transparent as compared to the patches that lacked carbopol. The evaluation parameters of transdermal patches were evaluated like (Weight variation, Thickness, Folding endurance, Moisture content, Drug content and In-Vitro Permeation study etc).

Keywords: Glibenclamide, Transdermal Drug Delivery System, Carbopol 934, Transdermal Patches.

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