Abstract

A PILOT STUDY-A RETROSPECTIVE STUDY ON PRESCRIBING PATTERN OF ANTIHYPERTENSIVE MEDICATION AND ADHERENCE TO JOINT NATIONAL COMMISSION -8 GUIDELINES IN A RURAL TERTIARY CARE INDIAN TEACHING HOSPITAL

Albin J. Enchiparambil*, Nithin Manohar R., Jomin George Joseph, Arunima G., Santhosh M. Mathews

ABSTRACT

Background: Antihypertensive medications are one among the most highly used drugs across the globe as well as in India, and their prescribing pattern will be erratic despite the various clinical guidelines. Few studies address the pattern and adherence to the standard treatment guidelines in India. This study aimed to review the prescribing pattern of antihypertensive medications in a rural tertiary care teaching Indian hospital and to investigate the adherence to the Joint National Commission-8 (JNC-8) guidelines on prevention, detection, evaluation, and treatment of hypertension in adults. Aim: To review the prescribing pattern of antihypertensive medications in a rural tertiary care teaching Indian hospital and to investigate the Adherence to the Joint National Commission-8 (JNC-8) guidelines on prevention, detection, evaluation, and treatment of hypertension in adults. Objectives: The objectives of this study were to review the prescribing pattern of antihypertensive medications in a rural tertiary care teaching Indian hospital and to investigate the adherence to JNC-8 guidelines on prevention, detection, evaluation, and treatment of HTN in adults.To assess the appropriateness of medication prescribed using JNC-8. Methods: A retrospective observational study was conducted among the participants from different inpatient wards who are aged >18 years, without gender restriction. The prescription pattern was reviewed and adherence to the JNC-8 guidelines was also assessed. A purposive sampling technique was adopted and descriptive statistics. Results: The data analysed insights the prescriptions are in accordance with JNC-8 guidelines (90%).Also, presence of inappropriate medicines according to JNC-8. Discussion: Surprisingly 10% of the patients who received treatment were pre hypertensive.With regard to the treatment the most commonly prescribed class of antihypertensive drugs were CCBs around 60%.Among the enrolled. By conducting a pilot study it shows majority (60%) of the patients showing hypertension in age group between 48-63 years old (i.e middle aged group). Among the enrolled participants 60% were male and 40% were female, which reveals that prevalence rate was higher in males during our study period. Among the enrolled population 90% adhered toJNC-8 guidelines and 10% not adhered to JNC-8 guidelines. Conclusion: Our study revealed that CCB was the most prescribed drug, and in spite of the only 90% adherence rate, treatment was effective in the majority of the population. The treatment outcome can be improved if the adherence rate is increased further.

Keywords: Adherence, antihypertensive, drug use review, JNC-8, outcome review.