Abstract

ANTI-BACTERIAL EVALUATION OF HERBS AND FORMULATIONS

Asma Manzoor*, Syed atif Raza, Uzma Niaz and Humayun riaz

ABSTRACT

Acne vulgaris is a chronic skin infection affecting the majority of Indian population. There are several internal and external factors responsible for this infection. The present study emphasizes on screening of medicinal plant extracts against acne causing bacteria and antioxidant activity of these plant extracts. Anti-bacterial activities of methanolic extracts of Azadirachta indica, Glycyrrhiza glabra, Calendula officinailis, Echinacea angustifolia was carried out using agar well diffusion method against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis. The results revealed that different plant extracts showed noticeable activity against Different test organisms. The plant extracts of Azadirachta indica, Glycyrrhiza glabra, Calendula officinailis, Echinacea angustifolia showed significant activity against bacillus subtilis with diameter of 15mm, 10mm, 10mm, 10.5mm inhibition zone respectively. The minimum inhibition concentration (MIC) was measured for these four potential plant extracts. The MIC values of extracts of Azadirachta indica, Glycyrrhiza glabra, Calendula officinailis, Echinacea angustifolia were comparable to the standard reference drugs isotretinoin.

Keywords: Acne vulgaris, Antibacterial, Minimum Inhibitory concentration, herbs, Pathogenicbacteria.