Abstract

HISTOMORPHOLOGY OF LIPOMA ARBORESCENS AND ITS CLINICAL SIGNIFICANCE: A CASE SERIES

Dr. Sahana V.V., *Dr. Suja Ajoykumar and Dr. Rajendra Prasad K.N.

ABSTRACT

Introduction: Lipoma arborescens is a rare proliferative lesion of synovium, characterised by fatty infiltration. Any synovium-lined joint may be involved, but the knee is the favoured site. It preferentially affects adult men and etiology is unclear. Objective: To histopathologically evaluate six rare cases of lipoma arborescens. Material and metbhods: Synovial biopsy specimens of patients with features of lipoma arborescens received in the Pathology laboratory, KIMS Hospital and Research Centre were analysed. Study duration was from July 2014 to July 2017. Detailed histopathological study of the sections were done. Relevant clinical and radiological findings were correlated. Results: In the present study six cases of lipoma arborescens was reported. Most common age group affected was between 30 to 50 years (66.66%). All were males and knee joint (83.33%) was most common joint involved. Swelling, pain and fever were presenting symptoms in all patients. Grossly all were grey yellow and showed multiple papillary projections. Microscopically all of them showed synovial hypertrophy, lymphoplasmacytic infiltration and adipose tissue. Conclusion: Lipoma arborescens is a pseudo-tumorous lesion, with distinct histomorphology possibly resulting from inappropriate fat deposition and degenerative articular diseases of joints. Histopathology is very useful diagnostic tool in diagnosing lipoma arborescens.

Keywords: Synovial biopsy, Pseudo-tumorous lesion, Adipose tissue.