SYNTHESIS OF TRIAZOLE DERIVATIVES OF 1H-IMIDAZO [4, 5-B] PYRIDINE
A. Jeyanthi*
ABSTRACT
Triazole is an important pharmacophore and shows various medicinal properties such as antimicrobial, antitubercular, anti-inflammatory, hypoglycemic, anticonvulsant and antidepressant activity The triazole fungicides include tebuconazole, propiconazole, epoxiconazole, metconazole, cyproconazole, triadimenol, flusilazole and paclobutrazole. At high concentrations (micro molar) the triazoles are fungicidal and at low concentrations (nanomolar), they are fungistatic.The schiff’s bases of triazoles show antibacterial as well as antifungal
activity.Triazolam is used as sedative and hypnotic and Bittertanol is used as broad-spectrum fungicide.
Keywords: Tebuconazole, Propiconazole, Epoxiconazole, Metconazole, Cyproconazole.
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