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Abstract

AGMATINE: A POTENTIAL BIOLOGICAL THERAPEUTIC EFFECT

Neha R. Binjhade*, Kamlesh J. Wadher and Milind J. Umekar

ABSTRACT

Agmatine also called as decarboxylated arginine are natural biosynthetic, product.Its freshly indicated that agmatine synthesized in mammals. Agmatine has more biological targets and signaling pathway. Agmatine has a broad therapeutic index which was applicable from 16 independent research group this gives attention to the preclinical and clinical evidences, this was highlights challenges and opportunities. This review is summarized the implication of agmatine in CNS and current research of agmatine in other systems of the body like cancer, cognitive disorder, cardio protectant effect. In cancer there is low effect of agmatine, in cognitive disorder high effect also the other research is carry on brain function. In cardioprotecton still research is continue.

Keywords: Agmatine, L-arginine, cardiovascular diseases, Anticancer.


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