Abstract

A COMPREHENSIVE REVIEW ON VITILIGO AND IT’S TREATMENT

Krutika S. Bobde*, Kanchan P. Upadhye, Parag A. Lekurwale and Rohit T. Durge

ABSTRACT

The present review includes the study of vitiligo, its different types and disorder at the clinical, pathophysiological and therapeutic levels and also summarize the information gathered about treatments available of the vitiligo. Vitiligo, a depigmenting skin disorder, is characterized by the selective loss of melanocytes, which in turn leads to pigment dilution in the affected areas of the skin. Vitiligo occurs worldwide with an estimated overall prevalence of less than 0.5% in population-based studies. The causes are unknown but might be involved genetic factor, oxidative stress, autoimmunity, cellular effect, environmental factor etc. primary aim is to bridge current knowledge at the clinical and investigative level, to point to the many unsolved issues, and to delineate future priorities for research. Many treatment have been used for some time; however we provide an overview of the currently known herbal, homeopathic, allopathic, ayurvedic medicine and yoga treatment for vitiligo. The light therapy and surgical management has a very good tool for the vitiligo. The traditional treatment along with novel approaches of therapy to increase the quality of patient life.

Keywords: Vitiligo, Leukoderma, Topical drug delivery, Phototherapy, Pigmentation, Immune system.