Abstract

DENGUE VIRAL INFECTION: A REVIEW

Sakshi Thapliyal, N. K. Singh and A. K. Upadhyay*

ABSTRACT

Dengue fever is a mosquito-borne illness caused by the dengue virus, which belongs to the genus Flavivirus and the family Flaviviridae. Dengue is widespread throughout the tropics and its transmission is strongly influenced by certain factors like rainfall, temperature, urbanization, and distribution of the principal mosquito vector Aedes aegypti. The viral infection caused may be asymptomatic or in the form of undifferentiated fever, dengue fever, dengue hemorrhagic fever, or dengue shock syndrome. Globally, dengue fever is responsible for 100 million new cases annually with 500,000 hospitalizations and 25,000 deaths. There is no vaccine available at present to prevent this disease. The increase in global cases is associated with urbanization, increased international travel, insufficient water supplies, and climate change. This article provides a general overview of dengue fever, the epidemiology of dengue infection, and covers the clinical features, pathogenesis, control, diagnosis, and treatment of these infections.

Keywords: .