INSIGHTS OF HYPHENATED MASS SPECTROSCOPIC TECHNIQUE
A Anusha Mary*, Dinesh R. Chaple, Kumar Pratyush, Abhidnya Deshmukh and Vaibhav Mohare
ABSTRACT
Liquid chromatography–mass spectrometry (LC-MS) is a technology of emerging importance in many fields like in the field of pharmacology, drug development, proteomics etc. LC-MS approaches have shown tremendous potential in the field of drug development. Here are limitations and caveats to be considered when implementing this technology into the clinical laboratory environment. A review of methodological approaches, applications, Instrumentation, and its various interface types are discussed in this paper.
Keywords: Liquid Chromatography, Mass Spectroscopy, Interface, Proteomics, Metabolomics.
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