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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

ANXIOLYTIC ACTIVITY OF METHANOLIC LEAVES EXTRACT OF OCIMUM SANCTUM IN ALBINO WISTAR RATS

M.Prasada Rao*, T.Susmitha, A.Aparna jyothi, P.Santhi swaroop ,B.Suvarna kumari, M.Srilatha, K.Anvesh, P.Jyothi

ABSTRACT

The anxiolytic activity of ocimum sanctum leaf (200.400mg/kg) extract was monitored using the Elevated plus maze method taking Diazepam(2mg/kg) as the standard.It was observed that the leaf extract decreased the elevated levels ,significantly when compared to the standard (p<0.001), The cxtract showed asignificant increase in the number of open arm entries and also decreased the time spent in the closed arm (p<0.001).Thus the result suggest that the methanolic leaf extract of ocimum sanctum is a reliable anxiolytic agent.

Keywords: Anxiolytic activity,ocimum sanctum leaf extract, Elevated plus maze, Diazepam.

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