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Abstract

ANTI GASTRIC ULCER ACTIVITY OF FICUS VIRENS LEAF IN WISTAR ALBINO RATS

M. Rama Devi*, N. Siva Subramanian, A.Tamilsevan, S.Anbazhagan, Umesh B Telrandhe

ABSTRACT

The effect of chloroform and methanolic extract of Ficus virens leaf was investigated in rats to evaluate the anti-ulcer activity by using ethanol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, pH, free acidity, total acidity and ulcer index. The results indicate that the ethanolic extract 200mg/kg significantly decreases the volume of gastric acid secretion, pH, free acidity, total acidity and ulcer index with respect to standard.

Keywords: virens Aiton, pyloric ligation, ethanol induced ulcer activity.


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