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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF APIXABAN BY RP-HPLC METHOD

Rajendra Satle*, Sanjay Bhavar and Ganesh Shinde

ABSTRACT

Objective of the present work is to develop and validate a simple, cost effective, sensitive and fast HPLC method for the analysis of Apixaban. Shimadzu LC-20AD HPLC with C18 (50mm x 4.6mm x 3μm) column is employed for the analysis using water: Acetonitrile (50:50, v/v) as mobile phase. Signal from Apixaban is detected at 259nm by UV Spectrophotometer. The proposed method is fully validated and found to be linear over a workable drug concentration, accurate, precise and robust. This fast and inexpensive method is suitable for research laboratories as well as for quality control analysis in pharmaceutical industries.

Keywords: Apixaban, Spectrophotometric method, Method development, Validation.

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