Abstract

ROLE OF VARIOUS ANTICOAGULANTS IN PREVENTION OF DEEP VEIN THROMBOSIS IN SURGERY DEPARTMENT

Soumya Sagar*, Mahadevamma L., P. Varshitha and Indumathi H.

ABSTRACT

Deep vein thrombosis is defined as the formation of one or more blood clots also known as a thrombus in one of the body’s large veins, most commonly in the lower limbs like the lower leg or calf. To assess the role of various anticoagulants in the prevention of deep vein thrombosis in the surgery department. This was a Prospective and Observational study that was performed on 80 patients which were conducted in the Surgery department of Sagar Multi-Specialty Hospital. This study included inclusion and exclusion criteria, this study was assessed and evaluated by a suitable statistical method. A total number of 80 patients was enrolled in the study in which 41 patients were male and 39 were female. Various age group was considered for the study and maximum participation was from the age group of 61-65 years old. The lowest participation was seen from the age group of 15-20 years old. Old Anticoagulant drug-like Inj Enoxaparin (81.8%) was most prescribed as surgical prophylaxis and New oral Anticoagulant drug-like Tab. Rivaroxaban (48.8%) was prescribed at the time of discharge of patients. 62 various surgeries were conducted out of which major surgeries were of orthopedics department for total knee replacement (right knee and left knee 6.3%). The patients were recovered from the surgery. No complications were seen from the new anticoagulant drug. In this study, we have found that various anticoagulant drugs were prescribed for various surgeries in which old anticoagulant drug like Inj Enoxaparin was prescribed post-surgically in the inpatient setting and new oral Anticoagulant drug-like Tab Rivaroxaban was prescribed during discharge period time as a prophylactic treatment for the prevention of DVT. New oral anticoagulant Tab Rivaroxaban is an oral drug that could be easily handled or administered by the patient compared to old anticoagulant Inj. Enoxaparin sodium was administered only subcutaneously. Hence it becomes difficult for a patient to administer the old anticoagulant drug by the patient themselves after the discharge.

Keywords: Deep vein thrombosis, anticoagulant drugs, Surgery.