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Abstract

AN OVERVIEW ON NANO LIQUID CHROMATOGRAPHY AND ITS APPLICATION

Ritesh R. Ojha*, Ashok E. Rathod, Soni N. Nara and Purnima D. Hamrapurkar

ABSTRACT

Nano liquid chromatography is a kind of microfluidic system used to resolve different pharmaceutical, clinical, biomedical, chiral, metabolic, protein, peptides and enatiomeric compound. It is used to detect compound in nanogram level by using nano litre of solvents hence ensuring low consumption of solvent and highly ecofriendly. Nano liquid chromatography uses low flow rate of 50 to 500 nano litres per min and high resolution,low sample detection are some of the advantages over traditional HPLC. Morever high cost of equipment may be some limitation although nano liquid chromatography is a newer technology ensures opening of new bridge to newer application for industry and laboratories.

Keywords: Nano liquid chromatography, Advantages, Instrumentation and Application of Nano liquid HPLC, Kennedy and Know equation.


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