Abstract

A REVIEW ON CHARACTERISTICS AND ANALYTICAL METHODS OF PITAVASTATIN: A POTENT STATIN DRUG

Shivani Sharma, Navdeep Singh*, Abhinay, Amar Deep Ankalgi, Arti Rana, Mahendra Singh Ashawat

ABSTRACT

The distinctive solutions are utilized within the treatment of hyperlipidemia join the fibric corrosive subordinates such as clofibrate, fenofibrate; bile corrosive sequestrants e.g. colestipol; cholesterol retention inhibitors e.g. ezetimibe; HMG CoA reductase inhibitors e.g. lovastatin, rosuvastatin, simvastatin and pitavastatin. Pitavastatin is novel medicate utilized within the treatment of hyperlipidemia. It must be given in single or in mixture with distinctive antihyperlipidemic specialists. Pitavastatin may be a exceptionally strong specialist called HMG CoA reductase inhibitors, or "statins." Pitavastatin lower the levels of low-density lipoprotein, or LDL and triglycerides within the blood, whereas expanding levels of high-density lipoprotein, or HDL. An colossal number of techniques counting Tall Execution Fluid chromatography (HPLC), UV–Visible spectroscopy are utilized for the assurance pitavastatin. There are different explanatory strategies utilized for sedate examination and these strategies have been approved agreeing to ICH rules (Q1A R2). Hence, this procedure can be securely utilized for standard pitavastatin quality control tests.

Keywords: Hyperlipidemia, Antihyperlipidemic drugs, Pitavastatin, Analytical methods, HPLC.