Abstract

A PROSPECTIVE STUDY ON PRESCRIBING PATTERN OF ANTIBIOTICS IN URINARY TRACT INFECTION IN A TERTIARY CARE HOSPITAL

*Ancy H. John, Bijurkar Triratna Rajeshwar, Ebcy Jose, Muhammed Ajmal PC, Dr. Sandra Sabu

ABSTRACT

Background Infection of the urinary tract is identified by growth of significant number of organisms of a single species in the urine in the presence of symptoms. Urinary tract infection is a common illness affecting both males and femlaes in almost all age groups. It is important to Intervene the progression by controlling the bacterial growth to prevent further complications like kidney infection by administration of antibiotics. Study on drug use evaluation on a tertiary care hospital was concluded. Objective  To study current trends in antibiotic prescription pattern in UTI patient.  To obtain the information and rational use of firstline choice of antibiotics.  To obtain information about age group which is affected with UTI.  To assess the appropriateness of medications prescribed for treating patients with UTI.  To assess the different route of administration and formulation resulting in better therapeutic outcome. Method and Methodology Prescribing pattern of antibiotics drug in tertiary care hospital in prospective observational study patient who were satisfying the inclusion criteria was enrolled into the study conducted for 6 month period. Data collecton form and other relevant source from medical record department are used as source of data and material. Result: 150 UTI cases were examined and 56% were females and 44% were males in 1 to 80 age group. In the management of UTI monotherapy was preffered and having 55% 0f management rate with monotherapy and 45% of management rate with combination therapy which includes 35% of two drug therapy, 8.66% of three drug therapy and 2% of more than 3 drug therapy. Nitrofurantoin was the most preferred class of drug and least preferred class of drug was glycopeptide antibiotic. Majority of patient were in age group between 40 to 59 (41%). More than 18% deviation from Indian guidelines was seen. Conclusion: The choice of antibiotic drug should be individualized based on patient complience, adverse effects,availability and costing factors,along with prevailing sensitivity pattern in the locality. Nitrofurantoin can be better alternative for uncomplicated UTI when compared to 3rd generation Cephalosporins. A 82% adherence to Indian guidelines was observed in the treatment.

Keywords: Antibiotic, Urinary tract infection, Prescription pattern.