Abstract

A COMPREHENSIVE REVIEW ON EMULGEL: MODERN APPROACH FOR TOPICAL DRUG DELIVERY

Rohit Durge*, Rahul H. Kasliwal and Yogesh N. Gholse

ABSTRACT

Considering NDDS (Novel Drug Delivery System), Emulgel is one of the recent technology used topically having characteristics of dual control release i.e. emulsion as well as gel. When gels and emulsions are used in combined form the dosage form are known as emulgel. Limitation of gels in the delivery of hydrophobic drugs through the skin. Overcome this limitation an emulsion based approach is being used so that even a hydrophobic therapeutic moiety can exhibit the unique properties of gels. Emulgel is prepared by different polymers which act as an emulsifying agent and thickening agent because the gelling capacity of these polymers give rise to stable emulsions by decreasing interfacial and surface tension while at the same time increasing the viscosity of the aqueous phase. Emulgel are having major advantages on novel vesicular systems as well as on conventional systems considering various aspects. The emulgel provide several favourable properties for its dermatological use such as greaseless, thixotropic, easily spreadable, emollient, easily removable, non-staining, water soluble, longer shelf life, transparent, bio-friendly and pleasing appearance.

Keywords: Emulgel, Emulsion based gel, Hydrophobic drugs, Topical drug delivery system.