Abstract

A VOYAGE FROM THE SEA TO CLINICAL STUDIES FOR INNOVATIVE ANTICANCER THERAPEUTICS DERIVED FROM MARINE ORIGINS

Pranjal C. Tidke*, Chetna M. Sangode and Milind J. Umekar

ABSTRACT

The aquatic ecosystem has proved to be a valuable source of compounds with unusual and special chemical properties, which can be used to enhance the potency and specificity of new drugs by molecular simulation and chemical synthesis. Cancer remains a growing public health threat, and amid recent developments in biomedical research and technology, new anticancer medicines are desperately needed. In both in vitro and in vivo models, marine compounds demonstrated their ability to mediate unique inhibitory actions on a variety of core cellular processes, including apoptosis mechanisms, angiogenesis, proliferation, and invasion, signalling their capacity for use as anticancer drugs. This review focus on the different marine drug structure, possible anticancer mechanism.

Keywords: Marine drugs, cancer.