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Abstract

EVALUATION OF SAPINDACEAE SPECIES FOR THEIR ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES IN EXPERIMENTAL ANIMALS

Chandra Prakash K.* and Shobha Rani S.

ABSTRACT

The present study aimed to evaluate the Analgesic and Anti-inflammatory activities of the alcoholic and aqueous extracts of Cardiospermum halicacabum and Dodonea viscosa, family sapindaceae in various experimental models as described in Hot Plate & Radiant Heat for Analgesic activity and Carrageenan Induced Paw oedema model for anti-inflammatory activity. The extracts were subjected for acute toxicity studies and found no mortality up to the dose of 2000mg/kg bodyweight hence 1/5th and 1/10th of the dose tested were used as the test dose and exhibited dose dependent biological property witnessing Analgesic and Anti-inflammatory properties of the plant. The phytochemical studies revealed the presence of various flavonoids, tannins, triterpenoids and saponins which might have contributed for the said activities.

Keywords: Cardiospermum halicacabum, Dodonea viscosa, Analgesic, Anti-inflammatory.


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