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ANTI MICROBIAL EVALUATION OF NEW OXADIAZOLE DERIVATIVES
Chilumula Nageshwar Rao*, K.Blessi Priyanka, J.Ravi, G.Dayakar*
ABSTRACT 5-(2-(2-(arylideneamino) oxazol-5-ylamino) benzoxazol-5-yl)-3- ((dialkylamino) methyl)-1, 3, 4-oxadiazol-2(3H)-thiones (XI) derivatives were evaluated for antimicrobial activity by using disc fusion method.The synthesized derivatives were evaluated for antibacterial activity and antifungal by using Ampicillin sodium and Clotrimoxazole as a standards. Among all compound XIa, XIb and XIh are more effective against bacteria. Among the series compound XIb is exhibited more inhibition against A.niger and C.albicans. Keywords: Bezoxazole, Oxadiazole, antimicrobial, antifungal, antibacterial. [Download Article] [Download Certifiate] |