Abstract

SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM – AN OVERVIEW

K. Arun Prasad*

ABSTRACT

The Self Nanoemulsifying Drug Delivery System (SNEDDS) is a Novel Drug Delivery System for Enhancement of water dissolvability of ineffectively water solvent medications. It is isotropic combination of oil, surfactant, cosurfactant atoms and it additionally containing co-dissolvable particle. It is Drug conveyance framework is thermodynamically and actively steady. The medication conveyance framework under mellow tumult is trailed by weakening of watery media, for example, GI liquid and it can from stable O/W Nanoemulsion. Having size of Globules is under 100nm. It is significant kind of Drug conveyance framework to keep up the compound dependability just as solvency of medication item. The Self Nanoemulsifying Drug Delivery System (SNEDDS) is significant application on BCS Class II and Class IV Drugs for improving water Solubility of inadequately water dissolvable medications. It is essential to forestall the interfacial strain and improving the disintegration just as ingestion pace of medication atom. It is Novel Drug Delivery System is Applicable for parenteral, Ophthalmic, intranasal and restorative medication conveyance framework. What's more, the current survey depicts Preparation, segments, component, of self Nanoemulsification, biopharmaceutical viewpoints, portrayal techniques and utilizations of self Nanoemulsifying drug conveyance framework (SNEDDS) For Enhancement of oral Bioavailability of ineffectively water solvent medications.

Keywords: Nanoemulsion, Miniemulsion, Submicron emulsion, Surfactant, Self-emulsifying system and Psedoternary Phase.