Abstract

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF ESCHERICHIA COLI ISOLATED FROM OUT-AND IN-PATIENTS AT DHAMAR HOSPITAL, YEMEN

Ahmed G. Al-Akydy*

ABSTRACT

E. coli has become a growing problem in hospitals, as well as communities around the world, therefore, it is important to have local hospital and community based knowledge of these strains causing infections and their sensitivity pattern to control their infections and to choose correct treatment regimens. Thus, the current study was carried out to evaluate the prevalence and antimicrobial susceptibility of E. coli isolated from different sources in patients at Authority General Dhamar hospital. A total of 100 isolates of E.coli were isolated from different sources, and identified, during a period of nine months, from October 2016 to June 20l7. Antimicrobial susceptibility testing to 9 antibiotics was performed by Kirby Bauer disc diffusion method. The majority of patients were males (85%). E.coli isolated from patients aged between 18- 45 years was the most resistance to antibiotics, where this group comprised 57% of patients. The E. coli was highly implicated in urine specimen (61%). E.coli was highly resistant to cefotaxime (71%), followed by azithromycin (62%), and least resistance was seen with meropenem (10%) and imipenem (7%). Multidrug resistance in E.coli was also observed in the present study. Regular surveillance of prevalence and antimicrobial susceptibility pattern of E. coli in hospitals, rational use for antibiotics and preventive measures are necessary to reduce resistance of E.coli against antibiotics. Also, there is a need to conduct periodic studies for the continuous monitoring of the E.coli outbreak at the hospital.

Keywords: Antibiotic, Resistance, E. coli, hospital, multiple antibiotic resistance, susceptibility.