Abstract

ASSESSING THE EFFICIENCY OF INTRAVENOUS IRON ALONE IN ANEMIC PATIENTS WITH CONGESTIVE HEART FAILURE

Gowtham Kumar Reddy P.*, Arjun Kumar Avvaru, SriVidya C., Sudharshan M., Sai Sushma M. and Krishna Kishore P.

ABSTRACT

Background & Aim: By World Health Organization, Anaemia is defined as the Haemoglobin concentration less than 13 (g/dL) for men or less than 12(g/dL) for women and CHF is a complex clinical syndrome resulting from any structural or functional impairment of ventricular filling or ejection of blood. The aim is to assess the efficiency of intravenous iron therapy alone in anemic patients with Congestive heart failure. Methodology: In this prospective cross sectional study, we collected data from 60 patients who are hospitalized with anemia with congestive heart failure and enrolled them for the study based on inclusion and exclusion criteria and classified the subjects into two groups, test and control based on the route of administration of Iron. Patients were monitored for 6 months after enrollment and data was analyzed for efficacy of IV alone therapy in anemic patients with congestive heart failure. Results: During the six months study period; we estimated the Hb and serum ferritin levels and of both groups at base line, after therapy interval and at first follow-up. At the baseline, the Hb was ( test: 5.88, control: 5.54) was after therapy (7.57) at first follow-up (12.34), respectively which have observed 15 Days duration extremely statistical significance difference observed between base line vs. first follow-up ( p <0.0005) respectively.And the HB level of standard group at base line (5.54)after therapy (7.16) at first follow-up (11,26), respectively which have observed 15 Days duration extremely statistical significance difference observed between base line vs. first follow–up ( p <0.68) respectively. Then We estimated the serum ferritin level of test group at base line (53.68) after therapy interval (98.25) at first follow-up (225,76), respectively which have observed 15 Days duration extremely statistical significance difference observed between base line vs.First follow –up (p<0.0005) respectively. And the serum ferritin level of standard group at base line (58.87)after therapy (91.87) at first follow-up (205,87), respectively which have observed 15 Days duration extremely statistical significance difference observed between base line vs.First follow –up (p <0.68) respectively. Conclusion: We conclude that Intra venous administration of iron sucrose to the patients with Anemia in congestive heart failure was found to be more effective in increasing Hb, Serum Ferritin, mitigating symptoms and increasing exercise capacity of the patient when compared with oral therapy.

Keywords: Congestive Heart Failure, Iron Deficiency Anemia, Intravenous Iron Therapy.