Abstract

A SYTEMATIC OVERVIEW: GASTRO ESOPHAGEAL REFLUX DISEASE

Ganesh P. Nalawade* and Mayur N. Raut

ABSTRACT

Gastro esophageal reflux disorder (GERD), conjointly referred to as acid reflux, could be a long-term condition wherever stomach contents come back up into the esophagus leading to either symptoms or complications. In the Western world between 10 and 20% of the population are suffering from GERD. The condition was initial represented in 1935 by Asher Winkel stein.[7] The classic symptoms had been described earlier in 1925. GERD is one of the most prevailing diseases in the world which might cause complications that embrace esophageal stricture and esophageal adenoid carcinoma. Several two challenges are related to GERD treatment. Initial proton pump inhibitors, the current standard of care for GERD, are ineffective for the majority of GERD patients who have non-erosive disease. Risk factors include obesity, pregnancy, smoking, hiatus hernia, and taking certain medicines. Clinical manifestations are heartburn, regurgitation (typical symptoms), cough, chest pain, asthma, hoarseness and throat clearing (atypical symptoms), which may be followed or not by typical symptoms. Complications include esophagitis, esophageal strictures, and Barrett's esophagus. The clinical treatment is useful in controlling the symptoms; however, the great problem is keeping the patients asymptomatic over time. Surgical treatment is indicated for patients who required continued drug use, intolerant to the drugs and with complicated kinds of GERD.

Keywords: gastro esophageal reflux disease, diagnosis, clinical treatment, surgery, fund complication of GERD.