Abstract

ANTIUROLITHIATIC POTENTIAL OF THE EDIBLE PLANTS AQUEOUS EXTRACT OF RADISH, WINTER MELON AND PSEUDOSTEM OF BANANA TREE: IN VITRO STUDY

Gurumoorthy Selvam, Murugesan Balasubramanian* and Ramasamy Subbaiya

ABSTRACT

Formation of stone in the kidney and intolerant pain is due to many factors. Though many treatments in the form of medication and/or surgery, laser and etc., are available in the market, they are giving temporary relief but not cure. Traditionally, certain vegetables and food materials are widely used for the treatment of the Urolithiasis. But knowingly or unknowingly people are consuming food as medicines in day-to-day life which rescue us from many illnesses. In this study, it is proposed to study the combinatorial effect of Radish, Winter melon and Pseudostem of banana tree extracts on kidney stone under in vitro condition. Antiurolithiatic potential of the extracts of Radish, Winter melon and Pseudostem of banana tree and synthetic kidney stone formation is studied under in vitro conditions using three critical assays such as crystal nucleation, aggregation and growth. The results of the in vitro assays showed that while increasing the volume of extracts readily prevented crystal nucleation, growth and aggregation. Extracts of Radish, Winter melon, and Stem of banana tree are found to be an effective diuretic, and acts as a promoter for inhibitors of calcium oxalate crystallization.

Keywords: Radish, Winter melon, Stem of a banana tree, Calcium oxalate, Nucleation, Crystal growth, aggregation, Urolithiasis and Kidney stones.