Abstract

A REVIEW ON TASTE MASKING TECHNIQUES FOR BITTER DRUGS

Salman Shaikh*, Rampal Singh Mandloi, Sujit Pillai, Nikhlesh Birla

ABSTRACT

Acceptability of any drug dosage form mainly depends over its taste i.e. mouth feel .drug molecule interacts with taste receptor on the tongue to give bitter, sweet or other taste sensation, when they dissolve in saliva. This sensation of taste is the result of signal transduction from the receptor organs for taste, commonly known as taste buds. Now a days most of the potent drugs that may be cardiac , analgesics, anti inflammatory, anti tubercular, anthalmentics, antibacterial ,anticoagulants, anti epileptics, antimalarials, anti neoplastics, anti thyroids, antiprotozoal, diuretics, histamine receptor antagonists, nutritional agents, opioids analgesics, oral vaccines and sex hormones, most of them are bitter in taste. So it becomes necessary to develop such a dosage for that must be acceptable in taste to patient especially in case of children or geriatrics.

Keywords: Taste, Taste buds, Taste Masking, Drugs, and Polymers.