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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

PREPARATION AND INVITRO EVALUATION OF CHLORZOXAZONE GASTRORETENTIVE FLOATING TABLETS

G. Vaishnavi*, A. M. Sateesh Kumar, Cheruvupalli Nagadev, Nakka Bharath, Shaik Mohammad Farooq and Syed Sunaina

ABSTRACT

The present study was carried out with an objective of preparation and in vitro evaluation of Hydroxy propyl methyl cellulose (HPMC K100), Xanthan gum as a polymers and sodium bicarbonate and citric acid as a gas generating agents with Chlorzoxazone as a model drug. The tablets were prepared by direct compression method. The effect of polymers concentration and viscosity grades of HPMC k100 on drug release profile was evaluated. An attempt was made to formulate floating tablets of Chlorzoxazone so as to increase the Gastric Residence Time (GRT) to improve the absorption.

Keywords: Gas retentive system, Floating tablets, Gas generating system, Floating drug delivery system, Effervescent tablets, Mucoadhesive drug delivery system .

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