Abstract

PHYSIO-CHEMICAL CHARACTERIZATION AND ANTIFUNGAL STUDY OF POLYHERBAL EXTRACT

Karpagam P.* and Manonmani G.

ABSTRACT

Synthetic antimicrobial drugs always result in Multidrug resistant bacteria, they are the solitary and most important threat to public health. They are associated with nosocomial infections. On consideration of toxicity and the adverse side effects of synthetic antimicrobial agents, the study accords the broadcast of herbs such as Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini for the current study based on its potent antimicrobial activity. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The antifungal activity of the screened polyherbal extract was found to be effective against A.niger. The results recommend the use of polyherbal extract at their best combination as a substitute to synthetic agents which effectively prevent the microbial infestation.

Keywords: Antifungal, FTIR, Polyherbal, Multidrug resistant bacteria.