Abstract

GC-MS ANALYSIS OF VARIOUS EXTRACTS FROM SEED KERNELS OF CAESALPINIA BONDUCELLA LINN

Annadurai Thenmozhi, Cyril Jane Shammah* and Narayanan Venkateshan

ABSTRACT

Caesalpinia bonducella (L.) is a prickly shrub belongs to the family Caesalpiniaceae commonly known as “Fever nut”, “Bonduc nut”, “Nicker seed” and “Kazharchikkaai” in Tamil. The seed kernels has been reported to possess several activities such as antipyretic, analgesic, antibacterial, antidiabetic, anticataract, antioxidant, anti-inflammatory, anticonvulsant, anticancer, antifungal and antihyperlipidemic. In the present study the ethyl acetate and ethanolic extract of Caesalpinia bonducella seed kernels has been subjected to GC-MS analysis. From GC-MS analysis 16 active components were detected from ethyl acetate extract and 11 active components were detected from ethanolic extract. The major phytochemical constituents present in ethyl acetate extract are 1,2-bis(trimethyl silyl)benzene (14.41%), 1,2-benzisothiazol-3-amine tbdms (13.20%), 2,4-dimethyl- benzo[h] quinoline (10.84%), trimethyl[4–(2-methyl-4-oxo-2-pentyl)phenoxy] silane (10.40%) and hexamethyl cyclotrisiloxane (8.99%). The major phytochemical constituents present in ethanolic extract was allomycin (31.84%), 2-chloro-4-(2-furanyl)-5-methyl-6-(2-thienyl pyrimidine) (28.19%), octanoic acid (12.75%), 1,2-bis(trimethylsilyl)benzene (6.39%), β-D-Lyxofuranoside,5-O-(β-D-lyxofuranosyl)-decyl- (4.64%).

Keywords: Caesalpinia bonducella, ethanolic extract, ethyl acetate extract, phytochemicals, GC-MS analysis.