Abstract

LOW-GRADE ENDOMETRIAL STROMA SARCOMA DIAGNOSIS AND MANAGEMENT

Mariyam Benayada*, Nadia Ch’michi, Youssef Essabbagh, Ismail Boujida, Oumaima Sarahdaoui, Honaida Mahfoud, Amina Lakhdar, Najia Zeraidi, Aicha Kharbach and Aziz Baidada

ABSTRACT

Endometrial stroma sarcoma (ESS) is a rare histological entity, accounting for only 1-2% of endometrial malignancies. Diagnosis is based on morphological and immunohistochemical criteria, with increasing use of molecular biology (FISH, PCR or sequencing by RNA -seq, CGH array, etc.). It is important that the specimens are quickly sent to pathology in a fresh state for their treatment. The pathology study concluded to the diagnosis of low grade ESS of malignancy, peritoneal location. In a woman over 40 years of age with imaging in favor of a single fibroid, it is necessary to fragment the piece in a suitable bag to avoid dissemination in the peritoneum. The objective of this study was to highlight the difficulty of evoking the diagnosis of ESS, especially in case of ectopic localization, to describe the clinical, radiological, histological and immunohistochemical aspects with a review of the literature.

Keywords: Endometrial stroma sarcoma, Low-grade, Hysterectomy.