Abstract

CORONARY ARTERY BYPASS SURGERY

Sakshi R. Kamble, Mayuri K. Lonare*, Jyoti B. Chavan and Deepak S. Musmade

ABSTRACT

(Lorenzen et al. systematic Reviews.http://doi.org/) Despite increasing survival, cardiovascular disease remains the primary cause of death worldwide with an estimated 7.4 million annual deaths. The main symptom of ischaemic heart disease is chest pain (angina pectoris) most often caused by blockage of a coronary artery. The aim of coronary artery bypass surgery is revascularisation achieved by surgically grafting harvested arteries or veins distal to the coronary lesion restoring blood flow to the heart muscle. Older evidence suggested a clear survival benefit of coronary artery bypass graft surgery, but more recent trials yield less clear evidence. We want to assess the benefits and harms of coronary artery bypass surgery combined with different medical therapies versus medical therapy alone in patients with ischaemic heart disease.

Keywords: Coronary artery bypass grafting, Ischaemic heart disease, Systematic review, Meta-analysis, Trial sequential analys.