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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NOVEL 2-SUBSTITUTED BENZIMIDAZOLE SCHIFF BASES AND ITS AZETIDINONE AND THIAZOLIDINONE DERIVATIVES

*Abhay Kumar Verma*, Rashmi kumari, Arun Kumar Singh (Sr.), Rinky Maurya ,Mukesh Chandra Sharma.

ABSTRACT

In the present study, a new series of 2-substituted benzimidazole schiff bases and its azetidinone and thiazolidinone derivatives were synthesized from O-phenylenediamine and P-amino benzoic acid. The synthesized compounds were screened for antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella typhi), antifungal (Candida albicans and Aspergillus niger), analgesic activity by tail-flick method and anti-inflammatory activity by carrageenan induced paw oedema method. The synthesized compounds showed significant activity of antibacterial, antifungal, analgesic and anti-inflammatory activity comparable to that of standard.

Keywords: Benzimidazole, Azetidinone, Thiazolidinone, Antibacterial, Antifungal, Analgesic, Anti-inflammatory.

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