Abstract

ANTIFUNGAL, ANTIMICROBIAL, ANTICANCER ACTIVITIES OF NIGELLA SATIVA

Soumitra Sahana*, Sariful Islam, Rojbul Islam, Indranil Chatterjee, Suman Kumar Nath, Rajeswar Das, Snehansu Biswas and Muslek Uddin Mazumder

ABSTRACT

Nigella sativa L. belongs to the botanical household of Ranunculaceae and is native to some components of the Mediterranean region and India as properly as different locations of comparable climates, hence it grows properly in Egypt. Nigella sativa (N. sativa) seed has been an compulsory dietary flavoring agent and herbal treatment for many illnesses for centuries in historic structures of medicine, e.g. Ayurveda, Unani, Arabic and Chinese Medicines. Many energetic elements have been remoted from N. sativa, simultaneously with dithymoquinone, thymol, carvacrol, nigellicine, nigellidine, alpha-hederin, nigellimine- N-oxide, thymohydroquinone and thymoquinone. It has been used as antihypertensive, anti-diarrheal, liver tonics, diuretics, digestive urge for food stimulant, anti-bacterial analgesics and in pores and skin disorders. Extensive research on N. sativa have been carried out via quite a number researchers and a huge spectrum of its pharmacological movements have been explored which may also consist of antimicrobial, anti-inflammatory, spasmolytic, gastro-protective, bronchodilator, hepato-protective, antidiabetic, anticancer, immunomodulator, analgesic, renal protective, antioxidant properties, and many others. In this paper, we summarized the Antifungal, Antimicrobial, Anticancer Activity of Nigella sativa.

Keywords: Nigella sativa L, Ranunculaceae, Treatment, Ayurveda, pharmacological, Antifungal, Antimicrobial, Anticancer.