Abstract

SOCIODEMOGRAPHIC AND HISTOPATHOLOGIC CHANGE OF CUTANEOUS LEISHMANIASIS IN SULAIMANI

Dr. Aseel Salahuddin Nooruldeen*, Dr. Abdullah M. Dawoud, Dr. Safaa Abdulzahra Ali and Dr. Darsim Muhammad Abdullah

ABSTRACT

Background: Cutaneous leishmaniasis (CL) is a zoonotic disease caused by infestation with protozoa of the genus Leishmania and the disease is endemic in Iraq and other countries in Middle East with fluctuation in their frequency, sometime reaching an epidemic state. The parasite is transmitted to the human by the bite of infected female sand fly. The hallmark of the disease (observed in 70% of the cases) is the presence of numerous amastigotes within the histiocytes and extracellular. Aim of study: To study the sociodemographic change of cutaneouse leishmaniasis in Sulaimani city and histopathological changes in cutaneouse leishmaniasis. Patients & Methods: This is descriptive study conducted in dermatology center in Sulaimani from November of 2014 to Jun of 2015 in which 158 patient taken with cutaneous leishmaniasis diagnosed clinically by two dermatology specialist. History and examination done for each patients. Biopsy done for 74 patients by punch biopsy(4 cm) send for histopathology department in Shorish hospital, Just result of 38 patients return back. Results: A total 158 patients the mean age of studied patients was 20±16.2. Male more than female. About two third of CL patients were living in rural areas and one third of them were living in urban areas. 69% of CL patients were Arabic (internally displaced patients), 30% CL patients were Kurdish and 0.6% patient was Turkmen. Half of cases were reported in winter season. More than two thirds (76.3%) of CL patients with biopsy had Leishman Donovan bodies and 26.3% of them had positive panniculitis. There were no significant differences between local resident and internally displaced patients (IDPs) infected with CL regarding duration, lesion number, perception, location and types (p>0.05). There was significant association between family history of CL and IDPs with (p=0.02). there was a significant association between implementing biopsy and IDPs with CL (P=0.02).

Keywords: Cutaneous leishmaniasis, Leishmania.