Abstract

NON-THERMAL PLASMA APPLICATIONS: IMPACT OF NONTHERMAL PLASMA TREATED WATER ON SOME BIOLOGICAL FUNCTIONS IN ALBINO RATS.

Shaimaa M. Eldeighdye*, Tarek M. Allam and Hanaa A. El- sayed

ABSTRACT

Background, atmospheric non-thermal plasma has attracted a great interest over the last decades and is currently is widely used in biomedical applications. Atmospheric plasma has proven itself as a safe and excellent in sterilization, wound healing and cosmetic tool upon topical treatment. This raise the important question whether oral administration of plasma-treated water (plasma activated water)/fluid is as safe and efficient as the topical treatment. Aims, this study is an attempt to assess the potential adverse effects of oral administration of non- thermal plasma treated water on some hematological and biochemical parameters in rats. Methods, tap water was exposed to low-cost air non-thermal plasma jet for 5, 10 and 15 minutes. Then, level of NO2, dissolved oxygen and pH were estimated in all water samples. Forty rats weighted between 120 -150gm were divided randomly into two groups. Control group (20 rats drinking tap water only) and treated group (20 rats drinking tap water exposed to plasma jet for 10 minutes only) for 60 days. Liver and kidney functions, full blood count, random blood sugar, both level of oxygen and pH of blood were established after short term (30 days) and long term (60 days). Results, Oral administration of plasma activated water for either short or long term did not affect the biological functions of liver or kidney. Also, blood counts of the treated groups did not exhibit significant differences compared to those of control group. Conclusion, this study showed that, non-damaging regimes exist in rats drunk plasma activated water, which can increase our therapeutic avenue for using non-thermal plasma treated water in very wide scale.

Keywords: Tap Water, non-thermal plasma, Plasma activated water(PAW), drinking (PAW) for long and short run, hematolgical and biochemical paramter, blood oxygen, water disolved oxygen, NO2 and pH.