Abstract

SAFETY AND EFFECTIVENESS OF EUPHORBIA PROSTRATA & CALCIUM DOBESILATE IN TREATMENT OF ALL GRADES OF HEMORRHOIDS

Garikapati Navya*, MD. Asiya Begum, N.V.S. Kameswari, T. Lakshmi Kavya, G. Sadasiva Rao and Dr. S. Uma Shanker

ABSTRACT

Background: The study entitled “Saftey and effectiveness of Euphorbia Prostrata and Calcium Dobesilate in treatment of all grades of hemorrhoids” was carried out in 50 patients. The Primary objective of this study were to assess the safety and effectiveness of drug in all grades of hemorrhoids and the secondary objective is assessment of incidence of hemorrhoidal disease in patients taking heavy spices and having family history and to assess the disease in idifferent age groups and gender. Method: This prospective observational study was conducted for a period of 6 months from 30 october 2018-30 march 2019 at lalita super specialities hospital, Guntur. Those patients who meet the study criteria were enrolled in to the study. A suitable data collection form was designed for use in the study. Disease condition was observed by signs and symptoms and physical examination. How well the euphorbia prostrata and calcium Dobesilate helped in reducing signs and symptoms was observed. All the relevant and necessary data for study was collected from treatment charts, interviewing patients and patient’s care takers and entered in data collection forms. All the collected raw data was entered in excel and for analysis purpose SAS 9.0 version was used. The statistical analysis was done in SAS Software by an appropriate statistical procedure like proc freq, proc means, proc tabulate, proc report, proc G-chart and to report the tables Out put delivery system was used. Results: Out of 55 cases, 50 patients completed the study protocol. After 2 weeks of treatment with the drug no one reported the symptoms in patients with grade 1 and grade 2 hemorrhoids. In grade 3, 3(15%) patients had some amount of symptoms, so they were asked to continue consuming Tablet for 2 more weeks. At the end of 4 weeks, 2 of the 3 patients completely relieved from symptoms, while the remaining patient continue to have symptoms and thus they were considered treatment failure. In grade 4, out of 3 patients no one got relieved from symptoms in the first two weeks of the treatment and they were asked to continue the treatment for two more weeks. And again no one got recovered from symptoms at the end of 4 weeks. Conclusion: The study indicates that two weeks of treatment with 100 mg of euphorbia prostrata and 500 mg of calcium Dobesilate could be adopted as one of the drug of choice for the treatment of grade I,II,III haemorrhoids.

Keywords: Hemorrhoids, euphorbia prostrata, calcium dobesilate.