Abstract

A CASE REPORT ON SHMIDT’S SYNDROME

*Anmariya Babu and Arya O.

ABSTRACT

Polyendocrine syndrome which can be interchangeably called as Schmidt’s syndrome is rare disorder which has a 1: 20,000 prevalence in general population and mostly affected in 3rd and 4th decade of life. It is a combination of autoimmune adrenal insufficiency (Addison’s disease) with autoimmune hypothyroidism and/or type 1 diabetes mellitus. It is little difficult to diagnose this disease as it has varying clinical presentations. Prompt diagnosis and treatment can prevent serious complications. Here we present a case of 50 yr old female patient came with complaints of generalized tiredness since 1 month, difficulty swallowing solid food and mild cough. She also has history of nausea, vomiting since 3 days. She had a past history of Type 2 DM, Dyslipidemia, Hypothyroidism. Her presentations attributing to gastric problems led to a late diagnosis. Physicians have to think about endocrine involvement where there is a confusing presentations. Most of the endocrine disorders have atypical components mimicking other differential diagnosis.

Keywords: Schmidt’s syndrome, autoimmune thyroiditis, polyglandular syndrome type 2, Addison’s disease, cortisol.