Abstract

REVIEW ON ORODISPERSIBLE LIQUISOLID COMPACT

Sumedha D. Vidhate*, Ulhas S. Surwase and Amitkumar K. Jadhav

ABSTRACT

Orodispersible liquisolid system is the combination of liquisolid technique and Orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of dug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water soluble drugs. Orodispersible tablets are given in order of provide fast action by disperse in the mouth, without the need of water and make them compliance for, pediatric and geriatric patients and to bypass the liver metabolism. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. ODTs render enhanced acceptability due to its patient compliance as well as improved bioavailailabity and stability. This article reviews recent trends undertaken to develop ODTs technologies, suitability of drug candidate and characterization of ODTs.

Keywords: Orodispersible, Evaluation Test, Stability etc.