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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

A REVIEW ON DETERMINATION OF RESIDUAL SOLVENTS BY USING DIFFERENT CHROMATOGRAPHY CONDITION IN OMEPRAZOLE API BY HEADSPACE GAS CHROMATOGRAPHY

Ramanpreet Kaur*, Pooja, Dr. Satvinder Kaur and Dr. Anu Jindal

ABSTRACT

This review is compilation of various techniques for measurement of residual solvent by headspace gas chromatography for Omeprazole drug. The measurement of residual solvent content is essential for all active pharmaceutical ingredients (API) according to the good manufacturing practices. In pharmaceutical samples, residual solvents can be monitored by using gas chromatography with headspace. Different chromatographic conditions include carrier gas, flow rate, detector temperature, injector temperature, loop temperature, transfer line temperature, GC cycle time. As per the ICH guidelines, validation parameters were performed for those developed methods.

Keywords: Omeprazole, Residual solvent, HSGC, ICH.

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